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We acknowledge the financial support in part by DCI Pilot Project, DOD grants (HT9425-24-1-0199, W81XWH-17-1-0143, W81XWH-15-1-0486, W81XWH-19-1-0842, W81XWH-20-1-0907) and NIH grants (R01GM124062, 1R21-AI149205)

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[PubMed: 22051327] 632

Hexapeptide-11 is composed of several amino acids, including alanine

25 Thus, while autophagy is clearly protective under physiological and early stress conditions, its chronic hyperactivation may become maladaptive

This study demonstrates a potential connection between anaemia and oxidative stress, which could accelerate the production of ROS in addition to reducing the ability of the antioxidant defence system caused by SNPs of enzymes